What's the easiest way to breed mice?

Put a male & female together in the same place (with some candlelight and a thimble of wine)- then just let nature take its course…

Breeding mice is generally pretty easy. I like to have the female in the cage for a while first before introducing the male, because its nice for the female to feel comfortable in her surroundings. A female mouse has an oestrous cycle of four days so she is almost certainly going to get pregnant in those four days. She will often go into oestrous (heat) apon being introduced to the male. You can check for pregnancy by looking for a plug in the vagin.a, but I find this is very difficult - it is only there for a short time after conception. I think its easier to just assume she got pregnant in the four days and moniter her size. The male can stay with her throughout her pregnancy - he wont harm the pups, infact he gets very paternal. Be careful to keep her calm and happy throughout her pregnancy. If she gets frightened, she can go a bit nuts and eat the pups. Mice can be quite canabilistic so its not that uncommon for them to eat their pups anyway. Gestation is about three weeks. My lab mice usually take twenty days.

oh, and mum will go into oestrus IMMEDIATELY after giving birth, so if you dont want anymore, get the dad out of there quick.

It’s not as easy as it sounds & be careful with it. I bred my mice awhile ago, & it took months. I kept buying male after female male after female & none would mate, & after i just about gave up two were pregnant & it led me to having around 68-74 mice at a time. They need like the right temperature, they have to get along, & it’s usually easier if you put two females with one male. You gotta be careful cause the males…they will eat the pups. & sometimes the moms will too. & when there pregnant & when they are mothers, try to keep them in a warm, quiet, none stressful enviornment. :x if any of that made sense.

The males are actually not any more inclined to eat the pups than the female (which isnt saying too much, since all rodents can be cannabilistic). If the male is present during the pregnancy he can recognise his offspring and be very protective of them.

No i know but if i didn’t seperate them quick enough then once the mother would leave to go get water or something, her pups would drag on her yeah after they fell off, it looked like he was just taking them back to the nest but after awhile i started noticing liddo cuts on each of their heads & feet. & they weren’t from the mother. The parents would even fight sometimes. So i’d seperate them. & plus she’d get pregnant again. :x