How: can I run a disk cleanup & defragmentation at the same time?

What is disk defragmentation ?

Have you ever done this to your computer? how long does it take? will it do anything bad to your comp?

Help!!! When I click on disk defragmenter and click defrag a message comes up "Disk defragmenter could not start" and I have ...

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My computer is saying that the file system structure on the disk is corrupt and unusable and I need to run the Chkdsk utility...

My computer is sayin that I dont have any space on disk c & I've tried to clean it up but it just anit workin

My computer keeps saying"Low Disk Space" but I clean both drives. I also removed several program to get more disk space & it ...

Every time I try to download a song, it says "Disk Problem." It was working before but now it's not. What happened and how do...

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Do all HTC phones open with and run on an operating system like a computer and everything like that or what is it supposed to...