Klinefelter's syndrome

It is speculative that Lili Elbe Klinefelter’s Syndrome, but she’s the only notable person I could find with it. She was an artist/model.

Lili Elbe, Danish transsexual, one of the first women to undergo a crude form of sexual reassignment surgery, through five operations which were completed by 1930. Fifteen months after her final surgery, she either died from complications or faked her own death to avoid the media attention. She is the subject of the 1933 book Man Into Woman, although it is likely she was never biologically male, but rather born intersexual, supposedy with rudimentary ovaries which would conflict with the speculative diagnosis of Klinefelter’s Syndrome.

That’s from here: http://www.changelingaspects.com/Life%20Stories/Short%20List%20of%20Transgendered%20Famous%20People.htm

And more on Lili Elbe here: http://encyclopedia.thefreedictionary.com/Lili+Elbe