A fairly standard HI Express. 70 rooms. Macon Way is a busy road taking traffic north from the roundabout which has alternative routes to junctions 16 and 17 of the M6, depending on whether you're coming from the south or the north, also 5 minutes' walk or less from Crewe Railway Station. It is next to a drive-through McDonalds.
This is certainly the swishest hotel in the area - AA 4-star rated, it is based on the Grade-1 listed 17th century Crewe Hall, and has 117 rooms, some in the old Hall, though most in the "contemporary" wing.
This is a smallish (20 rooms) Premier Inn located a few minutes' walk from the entrance to Crewe Railway Station. Note that there is another Premier Inn, Crewe West, located 2-3 miles away in Woolstanwood.
A 56-room Travelodge, located slightly out-of-the-way on the eastern edge of Crewe, though reasonably handy if you're visiting the Crewe campus of Manchester Metropolitan University.